2010 Fiscal Year Final Research Report
The Role of Maternal Aging in the Fetal Programming Hypothesis
| Project/Area Number |
21791550
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Mie University |
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Principal Investigator |
UMEKAWA Takashi Mie University, 医学部附属病院, 助教 (80422864)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 母体生活環境 / 食生活の欧米化 / 高脂肪食 / 胎児プログラミング / DOHaD / 高血圧 / 糖脂質代謝異常 |
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| Research Abstract |
In order to clarify the role of maternal excess fat intake in the fetal programming, we investigated the effects of a maternal high-fat diet before and during pregnancy on blood pressure and glucose and lipid metabolism in offspring. As a result, a maternal high-fat diet before and during pregnancy predisposes their offspring to hypertension and to the disturbance of glucose and lipid metabolism in adult life.
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