2010 Fiscal Year Final Research Report
Individual cervical cancer susceptibility and genomic structural variations of the defensin genes
| Project/Area Number |
21791566
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Nagasaki University |
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Principal Investigator |
MISHIMA Hiroyuki Nagasaki University, 大学院・医歯薬学総合研究科, COE研究員 (10513319)
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| Co-Investigator(Renkei-kenkyūsha) |
MIURA Kiyonori 長崎大学, 病院, 講師 (00363490)
阿部 修平 長崎大学, 大学院・医歯薬学総合研究科, 助教 (50549590)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 婦人科腫瘍学 / ヒトパピローマウイルス |
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| Research Abstract |
We hypothesized that the genomic structural variation of the defensin genes affects the individual variation of the cervical cancer susceptibility. Two groups, 200 patients with cervical cancer with persistent HPV infection and 200 control pregnant women, were compared in the distribution of genomic copy-number of the defensin genes. The results showed that the case samples have a tendency to be smaller in the copy-number of several defensin genes.
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[Presentation] 唇裂口蓋裂のGenome-wide association study.2010
Author(s)
引田正宣, 津田雅由, 佐々木健作, 三嶋博之, 田和加, 夏目長門, 内山健志, 平野明喜, 木下晃, 吉浦孝一郎
Organizer
第55回日本人類遺伝学会
Place of Presentation
大宮ソニックシティー,大宮OP15-075
Year and Date
2010-10-27
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