2010 Fiscal Year Final Research Report
Pathology of retinitis pigmentosa detected by adaptive optics scanning laser ophthalmoscopy
| Project/Area Number |
21791679
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Ophthalmology
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| Research Institution | Kyoto University |
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Principal Investigator |
OOTO Sotaro Kyoto University, 医学研究科, 助教 (10511850)
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| Co-Investigator(Renkei-kenkyūsha) |
HANGAI Masanori 京都大学, 大学院・医学研究科, 准教授 (70283687)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 臨床研究 |
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| Research Abstract |
We investigated the pathology of retinitis pigmentosa by high-resolution photoreceptor images using adaptive optics scanning laser ophthalmoscopy. Abnormal patterns of cone mosaic were observed in retinitis pigmentosa though regular cone mosaic was seen in all normal eyes. Cone density was significantly decreased in retinitis pigmentosa, compared with normal eyes. Cone density correlated with visual function (visual acuity and retinal sensitivity). From these data we developed a program for evaluating visual prognosis, and showed that AO-SLO is useful for evaluating the treatment effect in patients with retinitis pigmentosa.
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[Journal Article] High-resolution imaging of resolved central serous chorioretinopathy using adaptive optics scanning laser ophthalmoscopy.2010
Author(s)
Ooto S, Hangai M, Sakamoto A, Tsujikawa A, Yamashiro K, Ojima Y, Yamada Y, Mukai H, Ojima Y, Inoue T, Yoshimura N.
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Journal Title
Ophthalmology 117
Pages: 1800-1809
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