2010 Fiscal Year Final Research Report
Analysis of roles of glycosaminoglycans in keloid pathogenesis
| Project/Area Number |
21791742
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Plastic surgery
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| Research Institution | Kyoto University |
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Principal Investigator |
YAMAWAKI Satoko Kyoto University, 医学研究科, 時間雇用教職員 (70378777)
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| Project Period (FY) |
2009 – 2010
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| Keywords | ケロイド / 糖鎖 / GAG |
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| Research Abstract |
Excess accumulation of dermatan sulfate and chondoitin sulfate surrounding abnormal collagen bandles were found in keloid lesions. We propose that chondoitin sulfate plays a crucial role in the development of keloid lesions through the abnormal collagen fiber formation.
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