2011 Fiscal Year Final Research Report
Adiponectin improves survival rate of septic shock in mice model
Project/Area Number |
21791764
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Emergency medicine
|
Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
HARAGUCHI Go 東京医科歯科大学, 医学部・附属病院, 助教 (40361729)
|
Project Period (FY) |
2009 – 2011
|
Keywords | 集中治療医学 |
Research Abstract |
Adiponectin transgenic mice were improved survival rate with septic shock compared to wild type mice. Furthermore adiponectin anti-sense transgenic mice, low adiponectin mice were worsened survival rate. Adiponectin suppressed inflammatory signaling in cells involving with septic shock progression.
|