2011 Fiscal Year Final Research Report
Morphological characterization of type B synoviocytes in the temporomandibular joint focusing on expression of the muscle specific proteins
Project/Area Number |
21791783
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Morphological basic dentistry
|
Research Institution | Niigata University |
Principal Investigator |
INOUE Kayoko (NOZAWA Kayoko) 新潟大学, 医歯学系, 特任准教授 (90303130)
|
Project Period (FY) |
2009 – 2011
|
Keywords | 顎関節 / 滑膜 / 滑膜表層細胞 / 筋 |
Research Abstract |
Fibroblast-like type B synoviocytes(type B cells) in the temporomandibular joint(TMJ) are heterogeneous in their morphology and immunoreactivity. This study revealed that some of the type B cells expressed desmin, a muscle-specific intermediate filament, in adult rat TMJ. Immunocytochemical characteristics of the desmin-positive type B cell suggested that this cell does not have myogenic or contractile ability. In addition, their immunoreaction patterns and ultrastructures resembled those of a precursor of a capillary pericyte during angiogenesis.
|