2010 Fiscal Year Final Research Report
Cortical circuit of memory process enhanced by masticatory stimulation
| Project/Area Number |
21791815
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Functional basic dentistry
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| Research Institution | Kanagawa Dental College |
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Principal Investigator |
ONO Yumie Kanagawa Dental College, 歯学部, 准教授 (10360207)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 口腔生理学 / 咀嚼 / 記憶 / 海馬 / 脳磁図 / fMRI / 拡散スペクトラムイメージング |
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| Research Abstract |
We used multimodal brain imaging techniques to investigate how masticatory stimulation (chewing) increases cognitive function during working memory process. High time-resolution recordings of cortical activity by Magnetoencephalography revealed that memory acquisition activates the prefrontal cortex concurrently with the supplemental motor area and the supramarginal gyrus.
Moreover, gum chewing further increases the memory acquisition-related activity in the prefrontal cortex. These results suggest chewing as an easy and useful tool to activate the prefrontal cortex to maintain cognitive function.
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