• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2010 Fiscal Year Final Research Report

Characterization of stem cells from human exfoliated deciduous teeth (SHED) for mineralized tissue regeneration

Research Project

  • PDF
Project/Area Number 21791848
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Conservative dentistry
Research InstitutionNagoya University

Principal Investigator

NAKAMURA Sayaka  Nagoya University, 医学部附属病院, 医員 (40437033)

Project Period (FY) 2009 – 2010
Keywords再生医療 / 歯髄 / 乳歯
Research Abstract

Stem cells from human exfoliated deciduous teeth (SHED) have been identified as a novel population of stem cells. In this study, we focused on the characterization and possibility of mineralized tissue regeneration using SHED. These results suggested that SHED possesses adequate osteogenic/odontogenic capacity and is able to provide enough number of cells for clinical application easily because of high proliferation capacity. SHED that is generally discarded as medical waste and can be obtained without any invasion could be useful cell source for mineralized tissue formation.

  • Research Products

    (19 results)

All 2011 2010 2009

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (12 results) Book (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Regulation of the Wnt signaling pathways during cell culture of human mesenchymal stem cells for efficient bone regeneration.2011

    • Author(s)
      Katagiri W., Yamada Y., Nakamura S., Ito K., Hara K., Hibi H., Ueda M.
    • Journal Title

      Oral science Int. in press.

    • Peer Reviewed
  • [Journal Article] Promising cell-based therapy for bone regeneration using stem cells from deciduous teeth, dental pulp, and bone marrow.2010

    • Author(s)
      Yamada Y., Ito K., Nakamura S., Ueda M., Nagasaka T.
    • Journal Title

      Cell Transplant. Nov 5(Epub ahead of print)

    • Peer Reviewed
  • [Journal Article] Stem cells from human exfoliated deciduous teeth (SHED) enhance wound healing and possibility of novel cell therapy.2010

    • Author(s)
      Nishino Y., Yamada Y., Ebisawa K., Nakamura S., Okabe K., Umemura E., Hara K., Ueda M.
    • Journal Title

      Cytotherapy in press.

    • Peer Reviewed
  • [Journal Article] A feasibility of useful cell-based therapy by bone regeneration with deciduous tooth stem cells, dental pulp stem cells, or bone marrow-derived mesenchymal stem cells for clinical study using tissue engineering technology.2010

    • Author(s)
      Yamada Y, Nakamura S, Ito K, Sugito T, Yoshimi R, Nagasaka T, Ueda M.
    • Journal Title

      Tissue Eng Part A. (Epub ahead of print)

    • Peer Reviewed
  • [Journal Article] Stem Cell Proliferation Pathways Comparison Between Human Exfoliated Deciduous Teeth and Dental Pulp Stem Cells by Gene Expression Profile From Promising Dental Pulp.2009

    • Author(s)
      Nakamura S., Yamada Y., Katagiri W., Sugito T., Ito K., Ueda M.
    • Journal Title

      J Endod. Nov;35(11)

      Pages: 1536-1542

    • Peer Reviewed
  • [Presentation] 乳歯および永久歯歯髄細胞による骨再生・インプラント治療への応用2010

    • Author(s)
      中村さやか, 山田陽一, 伊藤憲治, 上田実
    • Organizer
      第132回日本歯科保存学会学術大会
    • Place of Presentation
      熊本
    • Year and Date
      20100604-20100605
  • [Presentation] Cell-based therapy with dental pulp stem cells for bone regeneration.2010

    • Author(s)
      Yamada, Y., Nakamura, S., Ito, K., Katagiri, W., Umemura, E., Hara, K., Hibi, H., Ueda, M.
    • Organizer
      International Association for Dental Research (88nd General session of the pan European region of IADR), Barcelona
    • Place of Presentation
      Spain
    • Year and Date
      2010-07-17
  • [Presentation] Proliferation of SHED and relation to Wnt signaling pathway.2010

    • Author(s)
      Katagiri, W., Yamada, Y., Nakamura, S., Ito, K., Katagiri, W., Umemura, E., Hara, K., Hibi, H., Ueda, M.
    • Organizer
      International Association for Dental Research (88nd General session of the pan European region of IADR)
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-07-17
  • [Presentation] Optimized study for dental pulp stem cell-based therapy by ready-to-use.2010

    • Author(s)
      Umemura, E., Yamada, Y., Nakamura, S., Ito, K., Katagiri, W., Hara, K., Ueda, M.
    • Organizer
      International Association for Dental Research (88nd General session of the pan European region of IADR)
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-07-16
  • [Presentation] Characterization of dental pulp stem cells for mineralized tissue regeneration.2010

    • Author(s)
      Nakamura, S., Yamada, Y., Katagiri, W., Ito, K., Umemura, E., Ueda, M.
    • Organizer
      International Association for Dental Research (88nd General session of the pan European region of IADR)
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-07-15
  • [Presentation] Characterization and possibility of bone regeneration for dental implant using dental pulp stem cells (DPSCs) and stem cells from human exfoliated deciduous teeth (SHED) as novel stem cell origin.2009

    • Author(s)
      Nakamura S., Yamada Y., Katagiri W., Sugito T., Ito K., Ueda M.
    • Organizer
      18th Annual Scientific Meeting of European Association for Osseointegration
    • Place of Presentation
      Monaco
    • Year and Date
      20090930-20091003
  • [Presentation] Clinical application using injectable tissueengineered bone for minimally invasive and aesthetic dental implant treatment.2009

    • Author(s)
      Yamada Y., Ito K., Nakamura S., Yoshimi R., Hibi H., Baba S., Ueda M.
    • Organizer
      18th Annual Scientific Meeting of European Association for Osseointegration
    • Place of Presentation
      Monaco
    • Year and Date
      20090930-20091003
  • [Presentation] 歯髄幹細胞による再生医療を用いたインプラント治療への応用-乳歯、永久歯歯髄幹細胞による骨再生パラダイムシフト-2009

    • Author(s)
      山田陽一, 伊藤憲治, 中村さやか, 片桐渉, 馬場俊輔, 上田実
    • Organizer
      第39回日本口腔インプラント学会総会
    • Place of Presentation
      大阪
    • Year and Date
      20090925-20090927
  • [Presentation] 乳歯および永久歯歯髄細胞の遺伝子発現プロファイルの比較検討2009

    • Author(s)
      中村さやか, 山田陽一, 片桐渉, 杉戸孝行, 伊藤憲治, 上田実
    • Organizer
      第130回日本歯科保存学会学術大会
    • Place of Presentation
      札幌
    • Year and Date
      20090611-20090612
  • [Presentation] 歯髄幹細胞による創傷治癒、骨再生医療への展開-乳歯・永久歯歯髄幹細胞の比較-2009

    • Author(s)
      山田陽一, 中村さやか, 片桐渉, 杉戸孝行, 西野雄大, 伊藤憲治, 上田実
    • Organizer
      第130回日本歯科保存学会学術大会
    • Place of Presentation
      札幌
    • Year and Date
      20090611-20090612
  • [Presentation] 幹細胞を用いた再生医療による新規歯周病治療法のパラダイムシフト-臨床経過から-2009

    • Author(s)
      山田陽一、中村さやか、伊藤憲治、日比英晴、上田実
    • Organizer
      第52回日本歯周病学会学術大会
    • Place of Presentation
      岡山
    • Year and Date
      20090515-20090516
  • [Presentation] 乳歯・永久歯由来歯髄幹細胞による顎顔面領域再生への可能性2009

    • Author(s)
      山田陽一, 伊藤憲治, 中村さやか, 片桐渉, 杉戸孝行, 吉見涼子, 西野雄大, 日比英晴, 上田実
    • Organizer
      第54回日本口腔外科学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2009-10-10
  • [Book] 実験医学(再生医療の最前線2010幹細胞の分化誘導と臨床応用 歯髄幹細胞の再生医療における可能性)(第3章)2010

    • Author(s)
      山田陽一、中村さやか、上田実
    • Total Pages
      127-133
    • Publisher
      羊土社
  • [Patent(Industrial Property Rights)] 乳歯歯髄幹細胞に特徴的な遺伝子発現群の利用2009

    • Inventor(s)
      山田陽一、中村さやか、上田実
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Number
      特願,2009-122379
    • Filing Date
      2009-05-20

URL: 

Published: 2012-02-13   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi