2011 Fiscal Year Final Research Report
Pulp regeneration by chemokine
| Project/Area Number |
21791872
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Conservative dentistry
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| Research Institution | National Center for Geriatrics and Gerontology |
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Principal Investigator |
IOHARA Koichiro 独立行政法人国立長寿医療研究センター, 口腔疾患研究部, 特任研究員 (60435865)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 歯髄再生 / G-CSF / 血管新生 / マイクロアレイ |
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| Research Abstract |
To examine the angiogenic/proangiogenic properties, gene expression profiles were analyzed by microarray and real-time RT-PCR. The expression of G-CSF was much stronger in pulp CD31-/CD146-SP cells compared with that in adipose, none marrow and artery CD31-/CD146-SP cells. Pulp regeneration after pulpectomy by transplantation of collagen with G-CSF.
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