2010 Fiscal Year Final Research Report
Development of the novel noninvasive bone augmentation technique
| Project/Area Number |
21791907
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Kyushu University |
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Principal Investigator |
JINNO Yohei Kyushu University, 歯学研究院, 助教 (40507779)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 骨増生 / 歯科用インプラント / スタチン / 非侵襲 / 骨 |
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| Research Abstract |
Within the limitation of our study, we suggest that a single-shot percutaneous injection of fluvastatin with a collagen-α-tricalcium phpsphate (αTCP) composite induces new bone formation in a vertical direction around and under the composite(calvarial bone of rat). However, it is very difficult to obtain new bone on the alveolar bone (rat, dog). Further study is needed for clinical application. (ideal concentration of fluvastatin, investigation of the novel drug delivery system)
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