2011 Fiscal Year Final Research Report
Development of high performance artificial bones for maxillofacial reconstruction
| Project/Area Number |
21791975
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Tohoku University (2010-2011)
The University of Tokyo (2009) |
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Principal Investigator |
IGAWA Kazuyo 東北大学, 大学院・歯学研究科, 大学院非常勤講師 (90512111)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 口腔顎顔面再建外科学 |
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| Research Abstract |
The ideal high performance artificial bone was developed by the fabrication of three-dimensional forms from tricalcium phosphate using a 3D inkjet printer incorporating the optimal design of pores to improve the mechanical properties and cell affinity, in conjunction with printing basic fibroblast growth factor on the pores to accelerate bone regeneration. This study indicated that printing bFGF on the pores of the three dimensional artificial bones stimulated the new bone formation in the beagle skull defects. It was suggested that the high performance artificial bone can become a new treatment modality for bone regeneration.
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