2010 Fiscal Year Final Research Report
Expression and functional analysis of TPX2 gene in human salivary gland tumors
| Project/Area Number |
21791998
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
SHIGEISHI Hideo Hiroshima University, 大学院・医歯薬学総合研究科, 助教 (90397943)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 細胞周期 / 悪性腫瘍 / 紡錘体形成 |
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| Research Abstract |
The mRNA expression of TPX2 and RHAMM was increased in malignant salivary gland carcinomas compared with that in normal salivary glands. Moreover, TPX2 and RHAMM expression was observed in the mitotic spindle at the mitotic stage of cell cycle. RHAMM expression was increased at the M phase of cell cycle. These results suggest that TPX2 and RHAMM play a significant role in growth of the tumor cells.
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Research Products
(11 results)
