2010 Fiscal Year Final Research Report
Periosteal expansion osteogenesis combined with bone morphogenetic protein
| Project/Area Number |
21792024
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Kyushu Dental College |
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Principal Investigator |
YAMAUCHI Kensuke Kyushu Dental College, 歯学部, 助教 (10364150)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 口腔外科学一般 |
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| Research Abstract |
The alveolar form at the experimental region was changed dramatically following lateral expansion with the β-TCP block. Newly formed bone was observed in the gap between the bone and the β-TCP block, as well as on the lateral surface of the block. Moreover, the replacement of large parts of the β-TCP with newly formed bone was observed in the β-TCP block area. The β-TCP block worked as space-maker under the soft tissue, including the periosteum, and also acted as a substitute for original bone and this bone substitute was effective material for bone augmentation in both methods. However, BMP induction for the gap between B-TCP block and original bone didn't work as stable accelerator for the bone formation. It seems that some mediums are needed to obtain stable results for new bone formation.
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