2010 Fiscal Year Final Research Report
Relationship between leptin and orofacial development in fetus.
| Project/Area Number |
21792082
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Niigata University (2010)
Kyushu University (2009) |
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Principal Investigator |
NAKAMURA Yuki Niigata University, 医歯学系, 助教 (70452779)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 発生・分化 / 胎児発育 / レプチン |
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| Research Abstract |
From previous research results related to this study clarified that leptin also acts on taste organ. We found that taste organ is also the site of action of leptin. The results of this experiment could not confirm the expression of leptin receptor in fetal mouse mandible. If no expression of leptin receptor in the jaw of a fetus, the possibility of direct action of leptin to the jaw development is considered to be low. However, the possibility that leptin is involved in the orofacial development mediated the central system, is a subject of future investigation.
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