2010 Fiscal Year Final Research Report
The role of interleukin 35, the novel cytokine, in the human periodontal tissue.
| Project/Area Number |
21792134
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Periodontal dentistry
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
MITANI Akio Aichi Gakuin University, 歯学部, 講師 (50329611)
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| Project Period (FY) |
2009 – 2010
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| Keywords | IL-35 / 歯周組織 / 制御性T細胞 / 歯学 / 免疫学 |
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| Research Abstract |
The subunits of IL-35 were detected higher in gingival tissue of patients with periodontitis compare with healthy volunteer. IL-35 protein was also higher in GCF of patients with periodontitis compare with healthy volunteer. Moreover, IL-35 may inhibit the osteoclastogenesis. These results suggest that IL-35 could have the protective role in progression of periodontitis.
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Research Products
(31 results)
