2010 Fiscal Year Final Research Report
Effects of vitamin C on experimental atherosclerosis induced by periodontitis
| Project/Area Number |
21792148
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Social dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
EKUNI Daisuke Okayama University, 大学院・医歯薬学総合研究科, 助教 (70346443)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 歯周病 / 動脈硬化 / ビタミンC / 酸化ストレス / ラットモデル |
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| Research Abstract |
In the periodontitis group, there was lipid deposition in the descending aorta and significant increases of oxidative damages compared to the control group. Vitamin C intake significantly decreased oxidative damages and changed oxidative stress-and atherosclerosis-related gene expressions.
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[Journal Article] Effects of periodontitis on aortic insulin resistance in an obese rat model.2010
Author(s)
Ekuni D, Tomofuji T, Irie K, Kasuyama K, Umakoshi M, Azuma T, Tamaki N, Sanbe T, Endo Y, Yamamoto T, Nishida T, Morita M.
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Journal Title
Lab Invest 90
Pages: 348-359
Peer Reviewed
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