2010 Fiscal Year Final Research Report
Preparation of Non-spherical Cell-containing Hydrogel Materials Using Microscale Aqueous Multi-phase Systems
Project/Area Number |
21800009
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Biomedical engineering/Biological material science
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Research Institution | Chiba University |
Principal Investigator |
YAMADA Masumi Chiba University, 大学院・工学研究科, 特任准教授 (30546784)
|
Project Period (FY) |
2008 – 2010
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Keywords | マイクロ・ナノデバイス / バイオマテリアル / ハイドロゲル / 細胞移植 |
Research Abstract |
Microfluidic techniques have been developed to prepare non-spherical hydrogel materials utilizing multiphase laminar flows inside microchannels. By mainly using alginate as the hydrogel substrate, we fabricated anisotropic hydrogel fibers with the cross section composed of multiple regions of different compositions, and non-spherical yarn-ball-shape hydrogel beads having a large surface-to-volume ratio. As applications, we successfully performed the guided cell growth and high-density cell cultivation, demonstrating the usefulness of the presented hydrogel materials.
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Research Products
(12 results)