2010 Fiscal Year Final Research Report
Synthetic and SAR studies of alchivemycin, novel antibacterial and antitumor polyketide
| Project/Area Number |
21880012
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Bioproduction chemistry/Bioorganic chemistry
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| Research Institution | Tohoku University |
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Principal Investigator |
ENOMOTO Masaru Tohoku University, 大学院・農学研究科, 助教 (90546342)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 有機合成化学 / 天然物化学 / 全合成 / alchivemycin / tetrahydro-1 / 2-oxazine-3 / 5-dione |
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| Research Abstract |
Alchivemycins possessing unprecedented framework exhibit antibacterial and antitumor activities. A model compound of alchivemycin core, unprecedented tetrahydro-1,2-oxazine-3,5-dione moiety, has been synthesized.
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