2010 Fiscal Year Final Research Report
Comprehensive understanding of alkaloid translocation and plant defense mechanism.
| Project/Area Number |
21880048
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied biochemistry
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| Research Institution | Kobe Pharmaceutical University |
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Principal Investigator |
SHITAN Nobukazu Kobe Pharmaceutical University, 薬学部, 助教 (20547880)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 植物 / アルカロイド / トランスポーター / ニコチン / 転流 |
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| Research Abstract |
Alkaloids play a key role in the plants defense mechanism. The major alkaloid of the Nicotiana species, nicotine, is translocated from the root to the vacuoles of leaves. In this study, two transporters, C215 and T408, were analyzed. C215 is expressed in the tonoplast of leaves, and transported nicotine. Overexpression of C215 induced the nicotine production. T408 is localized to plastid and play an important role in nicotine synthesis. These knowledge might enhance the production of valuable secondary metabolites and the molecular breeding of plant which is more resistant to insects.
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[Presentation] Involvement of multidrug and toxic compound extrusion (MATE) transporters in nicotine translocation in Nicotiana tabacum2010
Author(s)
Shitan N., Morita M., Ito S., Minami S., Sawada k., Montagu MV., Inze D., Rischer H., Goossens A., Oksman-Caldentey KM., Moriyama Y., Yazaki K.
Organizer
Plant Membrane Biology 15^<th> International workshop
Place of Presentation
オーストラリア、アデレード
Year and Date
20100900
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