2010 Fiscal Year Final Research Report
Analysis of neural circuit formation in the cerebral cortex
| Project/Area Number |
21890046
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | The University of Tokyo |
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Principal Investigator |
AKINORI Tokunaga The University of Tokyo, 医科学研究所, 助教 (70549451)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 神経発生 / 神経回路網 / 発生工学 |
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| Research Abstract |
The molecular mechanism of regulating the patterning of neural circuits in developing brain had remained unclear. Therefore we introduced the GFP tracer into developing mouse brain by in utero electroporation to visualize cerebrocortical neuronal cells and the circuits. This method was useful for analyzing the candidate genes concerned with neuronal differentiation and the circuitry formation. By using this method, we identified several functional genes and generated conditional knockout mice.
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Research Products
(8 results)
