Development of a novel electrode for the nervous system

2010 Fiscal Year Final Research Report

• Project/Area Number: 21890101
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Orthopaedic surgery
• Research Institution: Nagoya University
• Principal Investigator: OKUI Nobuyuki Nagoya University, 医学部附属病院, 病院助教 (70547554)
• Project Period (FY): 2009 – 2010
• Keywords: 脱神経筋 / 神経細胞 / basic fibroblast growth factor(FGF)

Research Abstract

The goal of this experiment is to evaluate transplantation of rat embryonic neurons into adult rat peripheral nerve and the effect of intramuscular administration of FGF-2 with neuron transplantation. We found that neuron transplantation into peripheral nerve formed functional motor units and injection of FGF-2 with neuron transplantation didn't prevent muscle atrophy.

Research Products

• [Presentation] Transplantation of Embryonic Neurons into Peripheral Nerve Forms Functional Motor Units (2011)
  • Author(s): Kurimoto, S, Tatebe, M, Yamamoto, M, Okui, N, Arai, T, Natsume, T, Iwatsuki, K, Hirata, H
  • Organizer: 2011 Annual Meeting of the Orthopaedic Research Society in Long Beach
  • Year and Date: 20110113-20110116