• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2010 Fiscal Year Final Research Report

Analysis of molecular mechanism of arteriovenous patterning

Research Project

  • PDF
Project/Area Number 21890124
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field General medical chemistry
Research InstitutionOsaka University

Principal Investigator

KIDOYA Hiroyasu  Osaka University, 微生物病研究所, 助教 (00543886)

Project Period (FY) 2009 – 2010
Keywords血管新生 / 血管再生 / 組織再生
Research Abstract

In this study, we analyze the apelin/APJ system to establish the new method of effective neovascularization therapy. In the skin of mouse embryo, apelin is expressed in artery and APJ is expressed in vein. Moreover we found that apelin produced by artery effect to APJ in vein and contribute to arteriovenous patterning.

  • Research Products

    (11 results)

All 2011 2010 2009 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (5 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model.2011

    • Author(s)
      Kumasawa K, Ikawa M, Kidoya H, Hasuwa H, Saito-Fujita T, Morioka Y, Takakura N, Kimura T, Okabe M.
    • Journal Title

      Proceedings of the National Academy of Sciences 108巻

      Pages: 1451-1455

    • Peer Reviewed
  • [Journal Article] Apelin induces enlarged and non-leaky blood vessels for functional recovery from ischemia.2011

    • Author(s)
      Kidoya H, Naito H, Takakura N.
    • Journal Title

      Blood 115巻

      Pages: 3166-3174

    • Peer Reviewed
  • [Journal Article] Maturation of blood vessels by haematopoietic stem cells and progenitor cells : involvement of apelin/APJ and angiopoietin/Tie2 interactions in vessel caliber size regulation.2009

    • Author(s)
      Takakura N, Kidoya H.
    • Journal Title

      Thrombosis and Haemostasis 101巻

      Pages: 999-1005

    • Peer Reviewed
  • [Journal Article] Induction and expression of anti-angiogenic vasohibins in the hematopoietic stem/progenitor cell population.2009

    • Author(s)
      Naito H, Kidoya H, Sato Y, Takakura N.
    • Journal Title

      The Journal of Biochemistry 145巻

      Pages: 653-659

    • Peer Reviewed
  • [Presentation] Role of microRNAs for tumor angiogenesis and endothelial function2010

    • Author(s)
      木戸屋浩康
    • Organizer
      第18回日本血管生物医学会学術集会/The 8th Korea-Japan Joint Symposium on Vascular Biology work
    • Place of Presentation
      大阪府大阪市 梅田スカイビル(招待講演)
    • Year and Date
      2010-12-02
  • [Presentation] 腫瘍血管形成を制御する新規標的miRNAの同定と機能解析2010

    • Author(s)
      木戸屋浩康
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪府大阪市 リーガロイヤルホテル
    • Year and Date
      2010-09-23
  • [Presentation] Role of specific microRNAs for tumor endothelial function and angiogenesis. 'Angiogenesis'2010

    • Author(s)
      木戸屋浩康
    • Organizer
      Molecular Mechanisms and Functional Interactions
    • Place of Presentation
      Kloster Seeon (Germany)
    • Year and Date
      2010-09-19
  • [Presentation] The possibility of the revascularization therapy by a neovascular maturation factor apelin2010

    • Author(s)
      木戸屋浩康
    • Organizer
      The 5th international symposium of institute network
    • Place of Presentation
      石川県金沢市KKI ホテル
    • Year and Date
      2010-06-24
  • [Presentation] Apelinによる腫瘍血管成熟化は癌免疫療法の効果を改善する2009

    • Author(s)
      木戸屋浩康
    • Organizer
      血管生物医学会
    • Place of Presentation
      東京都文京区東京大学
    • Year and Date
      2009-10-09
  • [Book] 細胞工学11月号12011

    • Author(s)
      木戸屋浩康
    • Total Pages
      1104-1112
    • Publisher
      秀潤社
  • [Remarks] ホームページ等

    • URL

      http://st.biken.osaka-u.ac.jp/

URL: 

Published: 2012-01-26   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi