2010 Fiscal Year Final Research Report
Application of Polyphasic Calcium Phosphates to Direct Pulp Capping
| Project/Area Number |
21890134
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Conservative dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
KIBA Wakako Osaka University, 歯学部附属病院, 医員 (10523087)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 歯学 / 覆髄 / リン酸カルシウム / dentin bridge / 象牙芽細胞 |
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| Research Abstract |
Poly-CaP is effective to induce hard tissue formation because of its Ca-releasing property from the soluble calcium phosphates phase on the surface. Poly-CaP was also found to support proliferation and to promote differentiation of odontblast-like cells on its surface. Activation of odontoblastic function is suggested to be involved in the effectiveness of Poly-CaP to induce hard tissue formation. Impregnation of resin into etched HAp surface, with production of no gap at the bonding interface, was seen for all adhesives. These results suggest that its usefulness for direct pulp capping.
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