2010 Fiscal Year Final Research Report
Development of the molecular target therapy for oral squamous cell carcinoma by tumor angiogenesis inhibit.
Project/Area Number |
21890168
|
Research Category |
Grant-in-Aid for Research Activity Start-up
|
Allocation Type | Single-year Grants |
Research Field |
Surgical dentistry
|
Research Institution | Yamaguchi University |
Principal Investigator |
ITASHIKI Yasutaka Yamaguchi University, 医学部附属病院, 医員研究 (70530236)
|
Project Period (FY) |
2009 – 2010
|
Keywords | Bevacizumab / S-1 / 血管新生阻害 / アポトーシス |
Research Abstract |
Because the combination of bevacizumab and S-1 which was a 5-FU-based anticancer agent which was the molecular target drug of the vascularization repressor showed a significant antitumor effect in the implanted nude mouse of the oral squamous cell carcinoma cell, HSC-2, it was suggested that it was with new Tumor dormancy therapy for oral cancer.
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