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2010 Fiscal Year Final Research Report

Elucidation of the bone formation mechanism through Akt-mTOR

Research Project

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Project/Area Number 21890194
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Functional basic dentistry
Research InstitutionNagasaki University

Principal Investigator

ROKUTANDA Satoshi  Nagasaki University, 大学院・医歯薬学総合研究科, 助教 (60549608)

Project Period (FY) 2009 – 2010
Keywords骨格形成機構 / Akt-mTOR / Runx2 / Stat1,3 / S6K / 4EBP1
Research Abstract

I clarified a function of Akt for the bone formation until now. Akt regulates a large number of signal molecules in the down stream. I decided to perform function elucidation for the frame formation mechanism of those signal molecules.

  • Research Products

    (3 results)

All 2011 2010 Other

All Journal Article (2 results) Remarks (1 results)

  • [Journal Article] Overexpression of CRK II increases migration and invasive potential in oral squamous cell carcinoma2011

    • Author(s)
      Shin-ichi Yamada, Souichi Yanamoto, Goro Kawasaki, Satoshi Rokutanda, Hisanobu Yonezawa Akiko Kawakita, Takayuki K Nemoto
    • Journal Title

      Cancer Letters

  • [Journal Article] Regulation of Tcf7 by Runx2 in chondrocyte maturation and proliferation2010

    • Author(s)
      Masaki Mikasa・Satoshi Rokutanda・Hisato Komori・Kosei Ito・Ying Sze Tsang・Yuki Date・Carolina A.Yoshida・Toshihisa Komori
    • Journal Title

      Journal of Bone and Mineral Metabolism

  • [Remarks] ホームページ等

    • URL

      http://naosite.lb.nagasaki-u.ac.jp/dspace/handle/10069/24743

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Published: 2012-01-26   Modified: 2016-04-21  

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