2010 Fiscal Year Final Research Report

Explore genetic factors associated with susceptibility to psychiatric disorders and psychiatric-drug responsiveness

Research Project

Project/Area Number	21890215
Research Category	Grant-in-Aid for Research Activity Start-up
Allocation Type	Single-year Grants
Research Field	Medical pharmacy
Research Institution	University of Shizuoka
Principal Investigator	KAZUYUKI Inoue University of Shizuoka, 薬学部, 講師 (90514589)
Co-Investigator(Renkei-kenkyūsha)	安藤奈津子静岡県立大学, 薬学部, 大学生鈴木絵莉静岡県立大学, 薬学部, 大学生
Project Period (FY)	2009 – 2010
Keywords	精神疾患 / 遺伝子多型 / 脆弱性
Research Abstract	It is known that genetic factors are related to susceptibility to psychiatric disorders and psychiatric-drug responsiveness. If these genetic factors are clearly identified, there is a possibility for administering appropriate medication to prevent psychiatric illness from increasing in severity. In order to find out the genetic factors between susceptibility to psychiatric disorders and psychiatric-drug responsiveness, this research attempted to accumulate gene polymorphism data of healthy Japanese population. Up to now, there has been no genetic frequency information in part of polymorphisms our examined on the Japanese population. The findings may be useful for investigating the genetic factors concerning susceptibility to psychiatric disorders and psychiatric-drug responsiveness in Japanese population.