2010 Fiscal Year Final Research Report
Correlation between the bone-remodeling and angiogenesis on the diploic vein
| Project/Area Number |
21890249
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Keio University |
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Principal Investigator |
TORIUMI Haruki Keio University, 医学部, 研究員(非常勤) (30528203)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 板間静脈 / 頭頸部微小循環 / 骨微小循環 / 骨代謝 / 骨リモデリング / 血管新生 / 頭痛 / 脳血管障害 |
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| Research Abstract |
To examine the development of the diploic veins in the calvarium, FITC-dextran was injected into the tail vein. The total area of the diploic veins showed a continuous, age-dependent development. We also measured the red blood cell (RBC) velocities in the diploic veins using an in vivo imaging technique and revealed RBCs with a significantly high velocity and unidirectional characteristics at the entrance route. The route passed from the basal periosteum of the cranial bone via the dura mater and into the diploic veins. Our findings indicate the existence of communications between intra- and extra-cranial circulation.
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