Evolution of STOP1 system for management of multiple stress tolerance

2023 Fiscal Year Final Research Report

• Project/Area Number: 21H02088
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Review Section: Basic Section 38010:Plant nutrition and soil science-related
• Research Institution: Gifu University
• Principal Investigator: KOYAMA Hiroyuki 岐阜大学, 応用生物科学部, 教授 (90234921)
• Co-Investigator(Kenkyū-buntansha): 井内 聖 国立研究開発法人理化学研究所, バイオリソース研究センター, 専任研究員 (90312256)
• Project Period (FY): 2021-04-01 – 2024-03-31
• Keywords: STOP1 / 環境耐性 / SAUR / 窒素吸収

Outline of Final Research Achievements

Higher plants adapt to various environmental stresses by resistant mechanisms, while those are often antagonistic. For example, STOP1 transcription factor, which was originally discovered in Arabidopsis, positively regulates tolerance to cellular acidification, and uses this mechanism to positively regulate submergence tolerance which induce cellular acidification. On the other hand, salt tolerance is positively controlled by STOP1, but drought tolerance is negatively and antagonistically controlled by STOP1. Salt accumulation in soil may be more likely to occur in dry areas, and this is an example of conflicting stress tolerances controlled by the same molecule. In this study, we revealed that crosstalk between regulatory proteins and/or transcription factors, which form gene family, with STOP1contributes to alleviate negative antagonistic effect of STOP1 in stress tolerance.

Free Research Field

植物栄養学

Academic Significance and Societal Importance of the Research Achievements

植物の環境耐性の分子機構を理解することは、持続可能な食料システムを実現するために重要です。この研究では、陸上植物の環境ストレス耐性を制御する遺伝子であるSTOP1が、どのようにして異なるストレス耐性を制御するか、コケやモデル植物を用いて調べました。複雑な制御機構が、調節タンパク質や転写因子などのほかのタンパク質との相互作用で行われていることと、それが植物により多様であることを明らかにしました。