Research on the regulation of electrochemically active biofilms

2023 Fiscal Year Final Research Report

• Project/Area Number: 21H02111
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Review Section: Basic Section 38020:Applied microbiology-related
• Research Institution: Tokyo University of Pharmacy and Life Science
• Principal Investigator: Kouzuma Atsushi 東京薬科大学, 生命科学部, 助教 (20634471)
• Project Period (FY): 2021-04-01 – 2024-03-31
• Keywords: 微生物電気化学 / バイオフィルム / 細胞外電子伝達 / 発現制御

Outline of Final Research Achievements

This study established the scientific and technological foundation for controlling the formation and activity of electrochemically active biofilms (EABFs), which are key to improving the performance of bioelectrochemical systems. Specifically, the research identified a novel transcription factor involved in the signal transduction system that activates EABF formation in Shewanella oneidensis MR-1 and developed a technique to promote EABF formation by activating this signal transduction system in an electrode potential-dependent manner.

Free Research Field

環境微生物学

Academic Significance and Societal Importance of the Research Achievements

本研究では電気化学活性細菌に特有と考えられる環境認識・応答メカニズムの一端を明らかにし、さらにそのメカニズムを応用したバイオフィルム制御技術を開発した。これらの成果は微生物における未知の生理機能と生存戦略の解明につながるだけでなく、産業利用上重要な微生物電気化学プロセスの高効率化にも寄与するものであり、学術的、社会的に意義あるものといえる。