2023 Fiscal Year Final Research Report
Electron transfer channel in the sugar recognition system assembled on nano gold particle
| Project/Area Number |
21K03452
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 13030:Magnetism, superconductivity and strongly correlated systems-related
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| Research Institution | Sophia University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
橋本 剛 上智大学, 理工学部, 教授 (20333049)
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| Project Period (FY) |
2021-04-01 – 2024-03-31
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| Keywords | NMR / muSR / 一次元スピン拡散 / 糖認識センサー / ボロン酸糖認識 |
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| Outline of Final Research Achievements |
Existence of 1D spin diffusion in the electrochemical sugar recognition system consisting of a nano-sized gold particle, a ruthenium complex and a phenylboronic acid was investigated by NMR and muSR. When sugar molecules are recognized by the phenylboronic site, the response of electrochemical voltammetry of the Ru site changes, enabling the system to work as a sensitive sugar-sensor. In this recognition process, the change in the electronic state at the boron site caused by sugar must be transferred to the Ru site via alkyl chains. We have utilized the muon-labelled electrons method and the proton NMR to find out a channel of the electron transfer from the phenylboronic acid site to the gold nano particle via 1D alkyl chain. We have observed significant decrease in the spin relaxation rates with increasing applied field. The result is discussed in terms of low dimensional spin diffusion.
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| Free Research Field |
磁性
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| Academic Significance and Societal Importance of the Research Achievements |
糖は生体におけるエネルギー源であり，殆どの生命現象に関与する。中でも生物の活動エネルギーである血液中のグルコースは，生命の維持に大きくかかわっており，インスリン等のホルモンによる濃度調整機構が不全となると糖尿病と診断される。糖センサーは医療において需要が高く，糖以外の分子も含め，高感度で高選択性を持つセンサーの開発は，現代社会において喫緊の課題の一つである。しかしながら，現時点で，分子認識が電気化学部位へどのように情報伝達されるのかと言う機構はほとんどわかっていなかった。今回、一次元スピン拡散の存在が明らかになったことで、新規センサー開発の一助となることが期待される、
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