Detection of several retinoids in river water

2023 Fiscal Year Final Research Report

• Project/Area Number: 21K04318
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 22060:Environmental systems for civil engineering-related
• Research Institution: Ritsumeikan University (2022-2023); University of the Ryukyus (2021)
• Principal Investigator: Sawada Kazuko 立命館大学, 総合科学技術研究機構, 研究員 (00772485)
• Project Period (FY): 2021-04-01 – 2024-03-31
• Keywords: レチノイド / 河川水 / クロロフィルa / LC/MS/MS

Outline of Final Research Achievements

To measure the concentration of retinoids in river water using LC/MS/MS, analytical conditions were established for eight retinoids and chlorophyll-a. To clarify the occurrence of retinoids in the rivers, the concentrations of retinoids was examined at 7 stations of Seta River and Daido River from February to April 2023.AtRA, 4-oxo-atRA, and retinol were detected at almost all sampling stations. Concentrations of atRA and 9cRA in March and April correlated with chlorophyll-a concentrations.

Free Research Field

環境工学

Academic Significance and Societal Importance of the Research Achievements

水環境中におけるRARにアゴニスト作用を示し得る化学物質の挙動を把握し、それらの存在に寄与する要因を調査することで、RARアゴニストによる水環境汚染の全容解明ならびに制御戦略の考案につながるものであり、ヒトが生活する上で必要不可欠である水の安全性の確保、および特に水への依存性が高い水生生物の生態系への健全性の保全に重要な貢献を果たすことが期待される。