Research for Rapid Extractive Separation Methods for Chemical Substances by means of Ionic Coextraction System

2023 Fiscal Year Final Research Report

• Project/Area Number: 21K05119
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 34020:Analytical chemistry-related
• Research Institution: Konan University
• Principal Investigator: Chayama Kenji 甲南大学, 理工学部, 教授 (10188493)
• Co-Investigator(Kenkyū-buntansha): 岩月 聡史 甲南大学, 理工学部, 教授 (80373033)
• Project Period (FY): 2021-04-01 – 2024-03-31
• Keywords: イオン液体 / 共抽出 / 色素 / 大麻代謝物

Outline of Final Research Achievements

When extraction is performed from an aqueous solution containing the substance to be extracted, separated, and concentrated by a technique that produces an ionic liquid that is insoluble in water and has no vapor pressure, it does not have the absorption toxicity of organic solvents, allows the use of plastic containers, and does not require shaking. This advantage is clarified using the example of the extraction of dyes in equilibrium theory. We then invented a disk for multiple specimens that enables extraction solely by centrifugal force from rotation. The research progressed to the point where it was possible to develop an apparatus to drive the discs and analyze the separated ionic liquid phase by preparative or direct spectroscopy. This extraction system can be applied to any substance extraction system, but we have established extraction methods for phosphate ions and DNA in environmental sample water.

Free Research Field

分析化学

Academic Significance and Societal Importance of the Research Achievements

今回の研究では、イオン液体生成を用いた、化学物質の抽出が、新たな自動抽出デバイスを創成できる可能性について明らかにした。データ駆動型社会のうち、化学から生み出される情報を加速する原動力となることが期待される。ケムインフォーマティクスの一段の飛躍は、デジタル化と結びつきにくい化学反応操作の自動化により大きく前進するものと考えられるが、これらの操作の中でも、最もハードルが高かった液液抽出の自動化を達成するイオン液体生成を利用する自動抽出装置はこのような目的をも達成するキーデバイスになるものと確信している。