2023 Fiscal Year Annual Research Report
Revealing the Role of Postnatal Theta Rhythm in Establishing Memory Consolidation Mechanism during REM Sleep
| Project/Area Number |
21K06419
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| Research Institution | University of Tsukuba |
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Principal Investigator |
Kumar Deependra 筑波大学, 国際統合睡眠医科学研究機構, 助教 (20747696)
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| Co-Investigator(Kenkyū-buntansha) |
船戸 弘正 筑波大学, 国際統合睡眠医科学研究機構, 客員教授 (90363118)
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| Project Period (FY) |
2021-04-01 – 2024-03-31
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| Keywords | Sleep / memory / Theta / NALCN / Neonates / Fear |
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| Outline of Annual Research Achievements |
This study reveals that in postnatal (P26) mouse pups, the REM sleep theta oscillation is necessary for contextual fear learning and memory consolidation. Dreamless mutant pups that display discreet theta oscillations during REM sleep display deficiency to learn fear and consolidate fear memory.
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