• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2022 Fiscal Year Research-status Report

房室輪関連頻拍の概念・診断法・治療法の確立

Research Project

Project/Area Number 21K08022
Research InstitutionGunma University

Principal Investigator

金古 善明  群馬大学, 医学部, 准教授 (60302478)

Co-Investigator(Kenkyū-buntansha) 中島 忠  群馬大学, 医学部附属病院, 講師 (40510574)
Project Period (FY) 2021-04-01 – 2024-03-31
Keywords発作性上室頻拍
Outline of Annual Research Achievements

研究では、発作性上室性頻拍症のなかでも、三尖弁輪を伸展する遅伝導路を介する房室結節リエントリー性頻拍及び三尖弁輪起源の心房頻拍の電気生理学的特徴を明らかにし、新たな電気生理学的診断法、アブレーション治療法を開発、さらにこれらを房室弁輪部頻拍と包括する頻拍概念を提唱することを目的としている。我々はこの2年間に順調に症例の蓄積を行い、本頻拍のsuperior type fast-slow AVNRT総計20例、inferolateral type fast-slow AVNRT総計7例、心房頻拍計総計7例の症例を経験した。我々は今回新たな電気生理指標を見出し、国際英文誌(Pacing and Clinical Electrophysiology)にアクセプトすることができた。概要は、fast-slow AVNRT及び心房頻拍に共通して観察しうる心室刺激後のV-A-A-V反応の両頻拍間の違いを見出し、鑑別診断に応用した。これによりより一層の診断精度の向上が期待できる。また、国際誌Reviews in Cardiovascular MedicineのGuest editorをつとめる機会を得て「Clinical electrophysiology: diagnosis and treatment」と題した特集号を編集し出版した。このなかで今回の研究成果を発表した。

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

現時点の研究成果を論文化した。

Strategy for Future Research Activity

時点において特に問題は見当たらないので、次年度以降も同様の研究計画を施行する予定である。

Causes of Carryover

コロナ禍のために一時期研究が停滞したが、次年度に繰り越して研究を行う予定である

  • Research Products

    (20 results)

All 2023 2022

All Journal Article (12 results) (of which Int'l Joint Research: 11 results,  Peer Reviewed: 12 results) Presentation (8 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Response to Para-Hisian Pacing in the Setting of Presence of a Concealed Nodoventricular/Nodofascicular Pathway2023

    • Author(s)
      Nagashima Koichi、Maruyama Mitsunori、Kaneko Yoshiaki、Nogami Akihiko、Mori Hitoshi、Sumitomo Naokata、Tanimoto Kojiro、Hayashida Satoshi、Wakamatsu Yuji、Hirata Shu、Hirata Moyuru、Okumura Yasuo
    • Journal Title

      JACC: Clinical Electrophysiology

      Volume: 9 Pages: 283~296

    • DOI

      10.1016/j.jacep.2022.10.022

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Novel Ablation Strategy Targeting the Slow Pathway Visualized by Ultrahigh-Resolution Mapping in Typical Slow-Fast Atrioventricular Nodal Reentrant Tachycardia2023

    • Author(s)
      Wakamatsu Yuji、Nagashima Koichi、Kaneko Yoshiaki、Mori Hitoshi、Tsutsui Kenta、Maegaki Masaharu、Sonoda Kazumasa、Otsuka Naoto、Hirata Shu、Hirata Moyuru、Kato Ritsushi、Sumitomo Naokata、Okumura Yasuo
    • Journal Title

      Circulation: Arrhythmia and Electrophysiology

      Volume: 16 Pages: ‐

    • DOI

      10.1161/CIRCEP.122.011497

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Efficacy of SubcutAneous implantable cardioVErter-defibrillators in ?18?year-old CHILDREN: SAVE-CHILDREN registry2023

    • Author(s)
      Mori Hitoshi, Sumitomo Naokata, et al.
    • Journal Title

      International Journal of Cardiology

      Volume: 371 Pages: 204~210

    • DOI

      10.1016/j.ijcard.2022.09.008

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Ventriculoatrial Block and His-His?Changes During Supraventricular?Tachycardia2023

    • Author(s)
      Wong Christopher X.、Higuchi Satoshi、Nagashima Koichi、Kaneko Yoshiaki、Gerstenfeld Edward P.、Scheinman Melvin M.
    • Journal Title

      JACC: Case Reports

      Volume: 6 Pages: 101593~101593

    • DOI

      10.1016/j.jaccas.2022.08.010

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Novel CACNA1C R511Q mutation, located in domain Ⅰ-Ⅱ linker, causes non-syndromic type-8 long QT syndrome2022

    • Author(s)
      Nakajima Tadashi、Kawabata-Iwakawa Reika、Tamura Shuntaro、Hasegawa Hiroshi、Kobari Takashi、Itoh Hideki、Horie Minoru、Nishiyama Masahiko、Kurabayashi Masahiko、Kaneko Yoshiaki、Ishii Hideki
    • Journal Title

      PLOS ONE

      Volume: 17 Pages: e0271796‐

    • DOI

      10.1371/journal.pone.0271796

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Discrimination of atypical atrioventricular nodal reentrant tachycardia from atrial tachycardia by the V‐A‐A‐V response2022

    • Author(s)
      Kaneko Yoshiaki、Nakajima Tadashi、Tamura Shuntaro、Nagashima Koichi、Kobari Takashi、Hasegawa Hiroshi、Ishii Hideki
    • Journal Title

      Pacing and Clinical Electrophysiology

      Volume: 45 Pages: 839~852

    • DOI

      10.1111/pace.14540

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Oozing-type rupture caused by right ventricular intramural hematoma after right ventricular infarction2022

    • Author(s)
      Sano Yukie、Kato Toshimitsu、Takama Noriaki、Hisanaga Etsuko、Matsumoto Naohiro、Amanai Shiro、Ishibashi Yohei、Aihara Kazufumi、Nagasaka Takashi、Koitabashi Norimichi、Kaneko Yoshiaki、Yokoo Hideaki、Ishii Hideki
    • Journal Title

      Journal of Cardiology Cases

      Volume: 26 Pages: 395~398

    • DOI

      10.1016/j.jccase.2022.08.008

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A narrow QRS complex tachycardia: What is the mechanism?2022

    • Author(s)
      Sakai Satoshi、Nagashima Koichi、Kaneko Yoshiaki、Maruyama Mitsunori
    • Journal Title

      Heart Rhythm

      Volume: 19 Pages: 1557~1558

    • DOI

      10.1016/j.hrthm.2022.05.018

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] What is the mechanism of tachycardia and an apparent atrioventricular nodal response during <scp>para‐Hisian</scp> pacing?2022

    • Author(s)
      Kobari Takashi、Kaneko Yoshiaki、Tamura Shuntaro、Hasegawa Hiroshi、Ishii Hideki
    • Journal Title

      Journal of Arrhythmia

      Volume: 38 Pages: 646~649

    • DOI

      10.1002/joa3.12743

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Acute myocarditis associated with COVID-19 vaccination: A case report2022

    • Author(s)
      Nagasaka Takashi、Koitabashi Norimichi、Ishibashi Yohei、Aihara Kazufumi、Takama Noriaki、Ohyama Yoshiaki、Yokoyama Tomoyuki、Kaneko Yoshiaki
    • Journal Title

      Journal of Cardiology Cases

      Volume: 25 Pages: 285~288

    • DOI

      10.1016/j.jccase.2021.11.006

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Atrioventricular ring tachycardias: Atypical fast-slow atrioventricular nodal reentrant tachycardia and atrial tachycardia share a common arrhythmogenic substrate - A unifying proposal2022

    • Author(s)
      Kaneko Y, Tamura S, Kobari T, Hasegawa H, Nakajima T, Ishii H. Atrioventricular ring tachycardias: Atypical fast-slow atrioventricular nodal reentrant tachycardia and atrial tachycardia share a common arrhythmogenic substrate - A unifying proposal.
    • Journal Title

      Rev Cardiovasc Med

      Volume: 23 Pages: 369

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Slow-fast echo/AVNRTにsuperior slow pathwayを介する逆伝導が混在し不規則な頻拍を呈した一例.2022

    • Author(s)
      田村峻太郎、金古善明、中島忠、長谷川寛、小針尭司.
    • Journal Title

      臨床電気生理

      Volume: 45 Pages: 135-142.

    • Peer Reviewed
  • [Presentation] Electrophysiological characteristics and catheter ablation of atypical fast-slow atrioventricular nodal reentrant tachycardia using an inferolateral left atrial slow pathway2023

    • Author(s)
      Yoshiaki Kaneko, Koji Fukuda, Tadanobu Irie, Hiroshi Shimizu, Shuntaro Tamura, Takashi Kobari, Hiroshi Hasegawa, Tadashi Nakajima, Hideki Ishii:
    • Organizer
      第87回日本循環器学会学術集会
  • [Presentation] Clinical and electrocardiographic features that lead to a diagnosis with epilepsy in genetically-diagnosed LQTS patients.2023

    • Author(s)
      Tadashi Nakajima, Shuntaro Tamura, Hiroshi Hasegawa, Takashi Kobari, Kentaro Ikeda, Nogiku Niwamae, Shoichi Tange, Masahiko Kurabayashi, Yoshiaki Kaneko, Hideki Ishii.
    • Organizer
      第87回日本循環器学会学術集会
  • [Presentation] Out-of-hospital cardiac arrest with severe electrolyte abnormality and hypoalbuminemia due to strict vegan diet: an unusual presentation2023

    • Author(s)
      上羽卓、天内士郎、児玉智華、滝沢大樹、石橋洋平、藍原和史、高間典明、小板橋紀通、金古善明、石井秀樹.
    • Organizer
      第87回日本循環器学会学術集会
  • [Presentation] Response to parahisian pacing in the setting of presence of a concealed nodoventricular/nodofascicular pathway2023

    • Author(s)
      永嶋孝一、丸山光紀、金古善明、他.
    • Organizer
      第87回日本循環器学会学術集会
  • [Presentation] 密度マッピングが緩徐伝導路部位内の電位の検出に有用であったファロー 四徴症術後心房頻拍の一例.2023

    • Author(s)
      長谷川寛、金古善明、田村峻太郎、小針尭司、石井秀樹.
    • Organizer
      第3回日本不整脈心電学会関東甲信越地方会
  • [Presentation] Electrophysiological characteristics and catheter ablation of atypical fast-slow atrioventricular nodal reentrant tachycardia using an inferolateral left atrial slow pathway2022

    • Author(s)
      Yoshiaki Kaneko, Koji Fukuda, Tadanobu Irie, Hiroshi Shimizu, Shuntaro Tamura, Takashi Kobari, Hiroshi Hasegawa, Tadashi Nakajima, Hideki Ishii:
    • Organizer
      ESC Congress 2022
    • Int'l Joint Research
  • [Presentation] 僅かな心電図変化をきっかけに原因を診断できた虚血性心疾患合併院外心停止の一症例.2022

    • Author(s)
      岩井龍太郎、藍原和史、児玉智華、滝沢大樹 、藤井 孝成、 天内士郎、久野貴弘 、長谷川寛 、小針尭司 、石橋洋平 、田村峻太郎、高間典明 、小板橋紀通 、 金古善明 、石井秀樹
    • Organizer
      日本循環器学会第266回関東甲信越地方会
  • [Presentation] 非侵襲的低体温療法中に発症した難治性心室細動の一例.2022

    • Author(s)
      磯部いの八、金古善明、藍原和史、藤井孝成、谷内亮太、佐井秀野幸恵、天内士郎、石橋洋平、長坂崇司、高間典明、小板橋紀通、石井秀樹.
    • Organizer
      第264回 日本循環器学会関東甲信越地方会

URL: 

Published: 2023-12-25  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi