Preventing Cardiovascular Disease in Young Adults

2023 Fiscal Year Final Research Report

• Project/Area Number: 21K08123
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 53020:Cardiology-related
• Research Institution: The University of Tokyo
• Principal Investigator: Kaneko Hidehiro 東京大学, 医学部附属病院, 特任准教授 (70468510)
• Co-Investigator(Kenkyū-buntansha): 藤生 克仁 東京大学, 医学部附属病院, 特任准教授 (30422306)
• Project Period (FY): 2021-04-01 – 2024-03-31
• Keywords: 循環器学 / 予防医学 / 疫学

Outline of Final Research Achievements

Using large-scale real-world data in Japan, we conducted a comprehensive analysis focusing on the association of modifiable risk factors with the risk of developing cardiovascular diseases. The results revealed that, even in young adults, modifiable risk factors such as hypertension, diabetes, and obesity are associated with an increased risk of various cardiovascular diseases, including heart failure, atrial fibrillation, ischemic heart disease, and stroke. Furthermore, age-specific analysis suggested that the relative association between these risk factors and the risk of developing cardiovascular diseases would be stronger in younger individuals compared to middle-aged and older adults. These findings underscore the importance of managing modifiable risk factors in young adults from the perspective of cardiovascular disease prevention and provide valuable epidemiological insights.

Free Research Field

循環器学

Academic Significance and Societal Importance of the Research Achievements

近年、日本を含む先進国において若年世代の循環器疾患増加が疫学的課題となっている。今回、我々が行った一連の研究は、この課題に焦点を当て、若年世代の循環器疾患予防のために肥満、高血圧、糖尿病などの修正可能なリスク因子のコントロールがとても重要であることを示したものである。今後、これらの研究をさらに発展させることで学術的成果を挙げるのみならず、上記のような社会的、疫学的問題の解決にもつながることが期待される。