Prospective observational study examining the financial toxicity and quality of life of medical intervention in breast cancer patients.

2023 Fiscal Year Final Research Report

• Project/Area Number: 21K10364
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 58010:Medical management and medical sociology-related
• Research Institution: Okayama University (2022-2023); National Cancer Center Japan (2021)
• Principal Investigator: Iwatani Tsuguo 岡山大学, 大学病院, 講師 (90771379)
• Project Period (FY): 2021-04-01 – 2024-03-31
• Keywords: 経済毒性 / 乳癌

Outline of Final Research Achievements

A total of 1558 patients who had undergone breast cancer treatment in Japan were included in the study. The objective financial toxicity was defined as economic toxicity when medical expenses exceeded 20% of household income, and the subjective financial toxicity was defined as Grade 1-3 on the COST scale.
Objective financial toxicity was evaluated as presence of economic toxicity in 271 (17.4%) of 1558 patients. Subjective financial toxicity was evaluated as financial toxicity in 1020 (65.7%) of 1552 valid responses.
There was a large discrepancy between the prevalence of objective financial toxicity and subjective financial toxicity.

Free Research Field

ヘルスアウトカムリサーチ

Academic Significance and Societal Importance of the Research Achievements

本研究から、経済毒性（Financial toxicity:FT）は客観的FTと主観的FTで有病率におおきな乖離があることが分かった。今回検討に用いた定義は、いずれも米国で一般的に用いられているものである。米国とは医療提供体制、公的医療保険を含む社会保障制度が異なるわが国においてFTを検討する際には、わが国の現状に合ったFTの定義を検討する必要性がある事が示唆された。