2023 Fiscal Year Final Research Report

Development of the functional brain imaging method which is tolerant against habituation - for various pathological aspects of higher brain dysfunction

Research Project

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Project/Area Number	21K12641
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Review Section	Basic Section 90110:Biomedical engineering-related
Research Institution	Gunma University
Principal Investigator	Kikuchi Senichiro 群馬大学, 大学院保健学研究科, 教授 (60323341)
Co-Investigator(Kenkyū-buntansha)	土屋謙仕長野保健医療大学, 保健科学部, 准教授 (10807423) 福田正人群馬大学, 大学院医学系研究科, 教授 (20221533) 武井雄一群馬大学, 医学部附属病院, 講師 (30455985) 桜井敬子群馬大学, 医学部附属病院, 技術専門員 (40868692)
Project Period (FY)	2021-04-01 – 2024-03-31
Keywords	脳機能計測法 / 脳活動 / 馴化 / 自発的回復 / 二重過程理論
Outline of Final Research Achievements	We developed a strong brain function assessment method using "dual-process theory" and "spontaneous recovery," irrespective of task characteristics. One study induced spontaneous recovery with a four-week test interval, revealing a minimum interval needed for observation. Another study divided subjects into negative and neutral stimulus groups, showing that emotionally stimulating stimuli during testing influenced habituation. These findings, presented at three conferences, suggest valuable insights for improving test designs.
Free Research Field	医工学
Academic Significance and Societal Importance of the Research Achievements	本研究は脳機能計測法のアーチファクトの一つである反復計測による脳活動の純化を抑制するよりよい検査デザインのための材料を提供したことが有用と考えられる。