Investigation on chemical reactions induced by discharge with historical atmospheric composition and application for controlled synthesis of bioactive molecules

2022 Fiscal Year Final Research Report

• Project/Area Number: 21K13906
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 14030:Applied plasma science-related
• Research Institution: Tohoku University
• Principal Investigator: Sasaki Shota 東北大学, 工学研究科, 助教 (90823526)
• Project Period (FY): 2021-04-01 – 2023-03-31
• Keywords: 大気圧プラズマ / 大気放電 / 五酸化二窒素 / 活性酸素種 / 活性窒素種 / 活性硫黄種

Outline of Final Research Achievements

This study aims to understand the gas- and liquid-phase chemical reactions induced by atmospheric discharge-generated reactive species, to precisely synthesize discharge-derived reactive species with unknown biological effects, and to identify new discharge-derived reactive species with high biological activity. Based on an understanding of the atmospheric discharge-induced reactions, we succeeded in on-site synthesis of dinitrogen pentoxide (N2O5), a reactive species with unknown biological effects. In addition, it was newly found that N2O5 can generate polysulfane from hydrogen sulfide and modify amino acids with oxidation and nitration. Furthermore, N2O5 was found to be a bioactive species that can be sensed by plants and induces physiological responses.

Free Research Field

大気圧プラズマ

Academic Significance and Societal Importance of the Research Achievements

五酸化二窒素の選択合成技術とその気相化学反応モデルの確立，五酸化二窒素という新規生理活性分子種の同定に至ったため，学術的意義は大きいといえる．また，100 W以下の電力消費で，周辺大気から，300 ppmの五酸化二窒素をその場で選択合成可能な本技術は，学術分野のみならず社会における五酸化二窒素の活用を大きく推進する画期的合成技術であり，社会的意義の大きい成果である．