Application Wheel-Shaped Cationic Complexes to Catalytic Molecular Transformations

2023 Fiscal Year Final Research Report

• Project/Area Number: 21K14627
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 33020:Synthetic organic chemistry-related
• Research Institution: Osaka University
• Principal Investigator: Nishii Yuji 大阪大学, 大学院工学研究科, 准教授 (70773787)
• Project Period (FY): 2021-04-01 – 2024-03-31
• Keywords: 有機分子触媒 / トリプチセン / ハロゲン / 芳香族化合物 / カチオン

Outline of Final Research Achievements

Based on the previous study on TripSMe-catalyzed aromatic halogenation reaction, new catalytic reactions were establish and a novel catalyst platform was developed. In particular; (1) DFT calculations revealed the effect of molecular structure and charge distribution on catalytic performance, (2) metal-free direct trifluoromethylthiolation reaction was developed, and (3) several boron cluster compounds were found to be effective catalyst platform for the aromatic halogenation reactions.

Free Research Field

有機化学

Academic Significance and Societal Importance of the Research Achievements

本研究の遂行により、機能性に優れた有機分子触媒の開発に向け、新たな設計指針を提案することができた。この成果は有機合成プロセスの効率化に貢献するとともに、従来法では構築の困難であった分子構造へのアクセスを可能とする。こうした観点から、有機光電子デバイスの開発や超分子化学、有機金属化学といった関連分野に波及効果を及ぼすものと期待できる。