2023 Fiscal Year Final Research Report
Development of Unique Reactions between Unusual Reactive Species and Organophosphorus Species, and Synthesis of Functional Molecules
| Project/Area Number |
21K14630
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 33020:Synthetic organic chemistry-related
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| Research Institution | Kumamoto University |
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Principal Investigator |
Arae Sachie 熊本大学, 大学院生命科学研究部附属グローバル天然物科学研究センター, 講師 (90754896)
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| Project Period (FY) |
2021-04-01 – 2024-03-31
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| Keywords | リン中心性不斉 / 環化異性化 |
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| Outline of Final Research Achievements |
We investigated the reactions between VQM and organophoosphorus chemical species for the synthesis of unique functional molecules containing phosphorus atoms. As a result, we found intramolecular cycloisomerization of o-alkynylarylbenzoheterole chalcogenides, intramolecular cyclization of o-alkynylarylphosphine, and intermolecular reaction of o-alkynylnapthol and triphenylphosphine. All of those reactions showed interesting reactivity and the obtained products exhibited unique physical properties.
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| Free Research Field |
有機化学
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| Academic Significance and Societal Importance of the Research Achievements |
有機リン化合物は，様々な分子中にみられる有用な元素である．しかしながら，リン原子の性質により，特異な構造や物性を有する有機リン化合物の合成は困難であった．これに対して本研究では，我々のこれまでの知見をもとに，ユニークな反応中間体であるVQMと，調整や入手が容易な各種有機リン化学種との反応を検討した．その結果，新たに3つのユニークな反応を見出すことに成功した．
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