Development of external stimuli responsive chiral reaction chemistry

2023 Fiscal Year Final Research Report

• Project/Area Number: 21K14647
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 34010:Inorganic/coordination chemistry-related
• Research Institution: Yokohama City University
• Principal Investigator: Hattori Shingo 横浜市立大学, 理学部, 助教 (90846726)
• Project Period (FY): 2021-04-01 – 2024-03-31
• Keywords: キラリティ / 白金(II)錯体 / 外部刺激 / 準安定状態 / 発光 / 超分子キラリティ

Outline of Final Research Achievements

In this study, we focused on [Pt(L)(solv)]+ (HL = 1,3-(2-dipyridyl)benzene) and aimed to form and control its aggregate structure and chiral aggregate structure. We clarified that [Pt(L)(solv)]+ can form p-p type aggregates (thermodynamic products) and Pt-Pt type aggregates (kinetic products). We also clarified that large aggregates with Metal-Metal-to-Charge-Transfer (MMLCT) transitions are formed in aqueous solution, and that chiral aggregates can be formed by adding chiral tartaric acid. We also clarified that [Pt(L)(solv)]+ forms chiral complexes with protein (HSA) and generates photoproducts (singlet oxygen) in response to external stimuli (light irradiation). We also discovered new metal complexes that undergo color and structural changes in response to external stimuli.

Free Research Field

光化学・錯体化学

Academic Significance and Societal Importance of the Research Achievements

本研究成果は、マクロな外部刺激とナノスケールの分子構造に結びつけている点から、新しい科学分野となりえる。外部刺激によって分光学的性質が変化する金属錯体結晶は、外部環境や揮発性有機化合物を可視化できる化学センサーといったデバイスへと発展することが期待できる。