2023 Fiscal Year Research-status Report
Applications of muon in cancer research
| Project/Area Number |
21K15583
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| Research Institution | High Energy Accelerator Research Organization |
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Principal Investigator |
PANT Amba・Datt 大学共同利用機関法人高エネルギー加速器研究機構, 物質構造科学研究所, 研究員 (60760121)
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| Project Period (FY) |
2021-04-01 – 2025-03-31
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| Keywords | Hypoxia / muonium / tumor / cancer |
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| Outline of Annual Research Achievements |
As proposed and planned, to achieve long-term goal of detection of the molecular oxygen in biosamples using muon method to apply the muon method in cancer research, the systematic studies were performed in water, buffer and derivatives of hemoglobin using the muon. As a next step, the detection of oxygen in biosamples (hemoglobin, blood plasma under physiological conditions) and inhomogeneous system of hemoglobin and blood plasma will be performed within the extended project period.
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| Current Status of Research Progress |
Current Status of Research Progress
3: Progress in research has been slightly delayed.
Reason
Even though, I proposed to study directly from biosamples (hemoglobin, blood plasma, etc.) but at the starting of this study the temperature dependent
oscillating spectra in water attracted the focus. Now we summarize those data that provides new insight into muon spectroscopy. It makes delay in progress.
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| Strategy for Future Research Activity |
So far, the temperature dependent behavior in water and buffer were understood. For further study these water and buffer data provides background information for study in biomolecules like hemoglobin and real tissues. In the remaining time of the project, detection of oxygen in biosamples under physiological conditions.
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| Causes of Carryover |
For muon experiments in biosamples.
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| Remarks |
One student - Mr. Roshan Pudasaini has completed his master thesis in physics under this project.
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Research Products
(12 results)
