New esophagus covered-stent with drug-elution concurently used for advanced esophagus cancer treatment

2023 Fiscal Year Final Research Report

• Project/Area Number: 21K15852
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 52040:Radiological sciences-related
• Research Institution: Showa University
• Principal Investigator: Harada Ken 昭和大学, 医学部, 講師 (90753898)
• Project Period (FY): 2021-04-01 – 2024-03-31
• Keywords: 食道ステント

Outline of Final Research Achievements

Esophageal stents can prevent the esophagus from perforation and patients from losing oral intake. Those can be fatal to patients with advanced esophageal cancer. In this study, we aimed to develop a new stent strut and cover material to reduce the risk of this medical device falling off into the stomach and perforation. This study revealed the issues with the current stent strut and its cover. In addition, as a new cover material, we found new technology integrating elasticity, adhesiveness, and drug-elution using nanotechnology.

Free Research Field

食道ステント開発

Academic Significance and Societal Importance of the Research Achievements

新たな食道ステントはこの20年間開発されていない。胃への脱落予防と、カバー材料の接着性は今までになく新たな発想である。さらにこの可能性を実現するために、独自の技術を用いてカバー材料を開発しており、学術的意義、社会的意義がともに高いと考えられる。