Epigenetic Regulation of Adipocyte Progenitor Cells

2022 Fiscal Year Final Research Report

• Project/Area Number: 21K19499
• Research Category: Grant-in-Aid for Challenging Research (Exploratory)
• Allocation Type: Multi-year Fund
• Review Section: Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
• Research Institution: Akita University
• Principal Investigator: Waki Hironori 秋田大学, 医学系研究科, 教授 (00466765)
• Project Period (FY): 2021-07-09 – 2023-03-31
• Keywords: 脂肪細胞

Outline of Final Research Achievements

The aim is to elucidate regulatory mechanism that controls adipocyte progenitor cells in adipose tissue that were newly identified by recent single cell analyses and lineage analyses. We conducted flowcytometry and epigenetic analyses on adipocyte progenitor cells in adipose tissue and identified a subset of progenitor cells that have new characteristics.

Free Research Field

代謝・内分泌

Academic Significance and Societal Importance of the Research Achievements

新知見で明らかになった生体内の脂肪細胞に分化する前駆細胞群について解析を応用し、その制御機構を明らかにする目的で、脂肪組織内の前駆細胞の解析を施行し新たな性質を有する脂肪前駆細胞の一群を見出した。