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2022 Fiscal Year Final Research Report

Tracking of defaulters from HIV treatment programs in developing countries

Research Project

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Project/Area Number 21K19657
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Review Section Medium-sized Section 58:Society medicine, nursing, and related fields
Research InstitutionKumamoto University

Principal Investigator

UENO Takamasa  熊本大学, ヒトレトロウイルス学共同研究センター, 教授 (10322314)

Project Period (FY) 2021-07-09 – 2023-03-31
KeywordsHIV-1/AIDS
Outline of Final Research Achievements

United Nations Programme on AIDS (UNAIDS) initiative has improved access to antiviral drugs worldwide, but this is insufficient for the 2030 AIDS Zero (UNAIDS report). Dropout from treatment programs is one possible reason, but few studies have tracked dropouts. In this study, we quantitatively analyzed the treatment performance of HIV-positive individuals across Tanzania. The results showed that the marked efficiency reached more than 95% for adults, but not 90% for children (including those infected from mother to child). Furthermore, we actively tracked dropouts by phone, SNS, and home visits, and were able to successfully link several dropouts to the treatment program. Based on the questionnaires and other data, we examined awareness-raising and intervention measures to encourage return to the treatment program.

Free Research Field

感染免疫学

Academic Significance and Societal Importance of the Research Achievements

国連エイズ合同計画(UNAIDS)は2030年AIDS Zeroミッションの達成を主導している。エイズによる死亡者の激減などの効果は認められたものの、アフリカ地域の新規感染者の減少は滞っている(UNAIDSレポート)。現状のHIV治療では感染者は服薬を継続する必要があるため、HIV陽性者数が増加するなかで「Treat for all」を継続することに対しては、財政的な問題など多くの懸念が提起されている。AIDS Zeroを実現するためには、服薬継続に依存しない新たな革新的なケア・治療プログラムの開発が喫緊の課題である。本研究では、現行の治療プログラムの実態と、そこから脱落するケースを追跡する。

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Published: 2024-01-30  

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