Development of a new method for applying dental adhesive materials to repair root fractures, enabling surface periodontal regeneration.

2023 Fiscal Year Final Research Report

• Project/Area Number: 21K21006
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Multi-year Fund
• Review Section: 0907:Oral science and related fields
• Research Institution: Niigata University
• Principal Investigator: Hamaya Keisuke 新潟大学, 医歯学総合研究科, 非常勤研究員 (30911599)
• Project Period (FY): 2021-08-30 – 2024-03-31
• Keywords: 歯根破折

Outline of Final Research Achievements

In Japan, the number of tooth extractions due to issues like cavities and gum disease is decreasing. However, "root fractures" are relatively increasing. This study is focused on regenerating the cementum along the fracture line on the surface of the adhesive material after repairing a root fracture and fully regenerating the periodontal ligament. The aim is to develop a method for applying an adhesive material for root fracture repair that has "biocompatibility and cell induction ability" and combines "strength and adhesiveness" for long-term function. Various materials used in engineering studies and in vitro analysis were combined with 4-META/MMATBB resin cement and applied to a rat root fracture tooth repair model. The results showed that hard and soft tissues were in contact with the material surface.

Free Research Field

歯科補綴学

Academic Significance and Societal Importance of the Research Achievements

8020推進財団の調査によると，日本の永久歯の抜歯原因の第3位は歯の破折である．経年的にう蝕や歯周病が減少している一方で，歯の破折による歯の喪失は相対的に増加している．従来，歯根破折の治療方法は経過観察か抜歯であったが，4-META/MMATBBレジンセメントにより，破折歯を修復し意図的再植が可能になった．しかしながら破折線に沿って残存する材料表面には歯周ポケットが残り，再び炎症を生じたり，材料の劣化により再破折が生じることがある．そこで新たな接着材料を開発することで，セメント質と歯根膜を完全に再生できれば．歯根破折歯修復歯の長期生存による咬合崩壊の予防にもつながり大きな意義があると考える.