Development of scientific principles on quantum molecular dynamics in confined nano-spaces

2014 Fiscal Year Final Research Report

• Project/Area Number: 22246022
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Fluid engineering
• Research Institution: Osaka University
• Principal Investigator: KAWANO SATOYUKI 大阪大学, 基礎工学研究科, 教授 (00250837)
• Co-Investigator(Kenkyū-buntansha): DOI Kentaro 大阪大学, 基礎工学研究科, 准教授 (20378798) ; HANASAKI Itsuo 大阪大学, 基礎工学研究科, 助教 (10446734) ; TSUJI Tetsuro 大阪大学, 基礎工学研究科, 助教 (00708670) ; SHINTAKU Hirofumi 大阪大学, 基礎工学研究科, 助教 (80448050)
• Co-Investigator(Renkei-kenkyūsha): TANIGUCHI Masateru 大阪大学, 産業科学研究所, 教授 (40362628) ; HIBINO Hiroshi 新潟大学, 医学部, 教授 (70314317) ; TACHIKAWA Masanori 横浜市立大学, 生命ナノシステム科学研究科, 教授 (00267410)
• Project Period (FY): 2010-04-01 – 2015-03-31
• Keywords: 量子・分子流動ダイナミクス / 制限ナノ空間 / マイクロ・ナノデバイス / 表面・界面

Outline of Final Research Achievements

In this study, we could get the new knowledge from the following three themes, focusing on fluid dynamics in confined nano-spaces from a viewpoint of quantum-molecular dynamics. Firstly, some promising methods are suggested to obtain the detailed information of DNA molecules, where elongation and separation of biomacromolecules were realized by effectively applying electrokinetic phenomena in nanofluidic channels. Secondly, transport phenomena induced by ion concentration difference and electroosmotic flow in nanopore devices were successfully detected by developing electrical measurement systems, and our results could contribute to the expansion of single molecule analysis technologies. Furthermore, a fundamental platform to clarify the neural transmission mechanism in cells and organelles was established. Thirdly, we succeeded to theoretically predict reaction dynamics by quantum mechanical approaches and achieved deep understanding on nano-scaled ion transport phenomena.

Free Research Field

分子流体力学