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2012 Fiscal Year Final Research Report

Search for a clue with contact of taste and texture-analysis of physical taste using model lingual epithelial cells

Research Project

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Project/Area Number 22300256
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Eating habits, studies on eating habits
Research InstitutionThe University of Tokyo

Principal Investigator

ASAKURA Tomiko  東京大学, 大学院・農学生命科学研究科, 特任教授 (20259013)

Co-Investigator(Kenkyū-buntansha) FUNAKI Junko  福岡女子大学, 人間・環境学研究科, 准教授 (60219079)
Project Period (FY) 2010 – 2012
Keywords味覚 / 持続性 / 表面プラズモン共鳴 / 物性 / 受容体
Research Abstract

Food texture and tastes have been classified into distinct categories. Taste is evaluated by not only the intensity but also its continuity. We constructed the devise that examines the interaction between lipid bilayer mimicked in taste cell surface and food components. Bitterness is lasting taste among five basic tastes. The bitterness masking compounds were purified from natural cheese. Free fatty acids were identified as key substances of bitterness masking.

  • Research Products

    (16 results)

All 2012 2011 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (6 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Identification of Bitterness-masking Cheese2012

    • Author(s)
      Homma R, Yamashita, H, Funaki J, Ueda R, Sakurai T, Ishimaru Y, Abe K, Asakura T
    • Journal Title

      J. Agric Food

      Volume: 60 Pages: 4492-4499

    • DOI

      DOI:dx.doi.org/10.1021/jf300563n

    • Peer Reviewed
  • [Journal Article] Global gene expression profiles in developing soybean seeds2012

    • Author(s)
      Asakura T, Tamura T, Terauchi K, Narikawa T, Yagasaki K, Ishimaru Y, Abe K
    • Journal Title

      Plantphysiol. Biochem.

      Volume: 52 Pages: 147-153

    • DOI

      DOIdx.doi.org/10.1016/j.plaphy.2011.12.007

    • Peer Reviewed
  • [Journal Article] Genetic tracing of the gustatory neural pathway originating from Pkd1l3-expressing type III taste cells in circumvallate and foliate papillae2011

    • Author(s)
      Yamamoto, K, Ishimaru Y, Ohmoto M, Matsumoto I, Asakura T, Abe K
    • Journal Title

      J. Neurochem.

      Volume: 119 Pages: 497-506

    • DOI

      DOI:10.1111/j.1471-4159.2011.07443.x

    • Peer Reviewed
  • [Journal Article] Human sweet taste receptor mediates acid- induced sweetness of miraculin、Proc.2011

    • Author(s)
      Koizumi, A, Tsuchiya A, Nakajima K, Ito K, Terada T, Shimizu-Ibuka A, Loic, B, Asakura T, Takumi M, Abe k
    • Journal Title

      Natl. Acad. Sci.

      Volume: 108 Pages: 16819-16824

    • DOI

      DOI:10.1073/pnas.1016644108

    • Peer Reviewed
  • [Journal Article] Identification and Modulation of the Key Amino Acid Residue Responsible for the pH Sensitivity of Neoculin, a Taste-Modifying Protein.2011

    • Author(s)
      Nakajima K
    • Journal Title

      PLoS One

      Volume: 6 Pages: 274-278

    • DOI

      DOI:10.1002/ffj.2073

    • Peer Reviewed
  • [Journal Article] Analysis of the interaction of food components with model lingual epithelial cells: thecase of sweet proteins. 、Flavour Fragr.2011

    • Author(s)
      Asakura, T, Miyano M, Yamashita H, Sakurai T, Nakajima K, Ito K, Misaka T, Ishimaru Y, Abe K
    • Journal Title

      Flavour Fragr. J

      Volume: 26 Pages: 274-278

    • DOI

      DOI:10.1002/ffj.2073

    • Peer Reviewed
  • [Journal Article] Non- acidic compounds induced the sweetness of neoculin a Taste-Modifying Protein2011

    • Author(s)
      Nakajima, K, Koizumi A, Iizuka K, Ito K, Morita Y, Koizumi T, Asakura T, Shimizu-Ibuka A, Misaka T, Abe K
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 75 Pages: 1600-1602

    • DOI

      DOI:10.1271/bbb.110081

    • Peer Reviewed
  • [Presentation] アカゲザル味覚関連遺伝子群の茸状・有郭乳頭株味蕾における発現解析2012

    • Author(s)
      阿部美樹
    • Organizer
      日本農芸化学会2012年度大会
    • Place of Presentation
      京都女子大学(京都)
    • Year and Date
      2012-03-24
  • [Presentation] ヒト上皮ナトリウムチャンネ ル活性化剤S3969の蛍光膜電位測定による活性評価2012

    • Author(s)
      松田龍星
    • Organizer
      日本農芸化学会2012年度大会
    • Place of Presentation
      京都女子大学(京都)
    • Year and Date
      2012-03-24
  • [Presentation] シロイヌナズナ由来シグナル ペプチドぺプチダーゼ(AtSPP)の過剰発現株を用いた網羅的遺伝子発現解析2012

    • Author(s)
      養田直倫
    • Organizer
      日本農芸化学会 2012年度大会
    • Place of Presentation
      京都女子大学(京都)
    • Year and Date
      2012-03-24
  • [Presentation] チーズの苦味抑制活性とその起因となる遊離脂肪酸の解析2012

    • Author(s)
      本間亮丞
    • Organizer
      日本農芸化学会 2012 年度大会
    • Place of Presentation
      京都女子大学(京都)
    • Year and Date
      2012-03-23
  • [Presentation] 味覚修飾タンパク質ネオクリ ンのシステインバリアント作製とその機能 解析2012

    • Author(s)
      金田康平
    • Organizer
      日本農芸化学会 2012 年度大会
    • Place of Presentation
      京都女子大学(京都)
    • Year and Date
      2012-03-23
  • [Presentation] 味覚修飾タンパク質ネオクリンにおけるpH依存的構造変化のNMRによる検出2012

    • Author(s)
      小泉太一
    • Organizer
      日本農芸化学会 2012年度大会
    • Place of Presentation
      京都女子大学(京都)
    • Year and Date
      2012-03-23
  • [Book] コメのアスパラギン酸プロテアーゼー機能 解析と食品加工への応用-2012

    • Author(s)
      朝倉富子 阿部啓子
    • Total Pages
      341
    • Publisher
      三共出版株式会社
  • [Book] 味覚受容体2011

    • Author(s)
      朝倉富子
    • Total Pages
      56
    • Publisher
      社団法人生命科学振興会「医と食」編集部
  • [Remarks]

    • URL

      http://park.itc.u-tokyo.ac.jp/tastescience/index.html

URL: 

Published: 2014-08-29  

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