2012 Fiscal Year Final Research Report
Development of Gene Regulatory Network Analysis Methods for Revealing Cell Differentiation Processes
Project/Area Number |
22310125
|
Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
System genome science
|
Research Institution | Osaka University |
Principal Investigator |
MATSUDA Hideo 大阪大学, 情報科学研究科, 教授 (50183950)
|
Co-Investigator(Kenkyū-buntansha) |
TAKENAKA Yoichi 大阪大学, 情報科学研究科, 准教授 (00324830)
|
Project Period (FY) |
2010 – 2012
|
Keywords | 遺伝子ネットワーク / 細胞分化 / ベイジアンネットワーク |
Research Abstract |
We constructed a mathematical model for expressing gene regulatory relationships, based on gene regulatory networks, on multiple cell differentiations. We successfully explored several regulatory genes appeared in both of the two cell differentiations of mouse adipocytes and osteoblasts. We developed a parallel processing method on massively parallel servers to reduce a large amount of computational costs of the processing.
|