2012 Fiscal Year Final Research Report
Development and application of high-performance separation analytical methods for the components of single cells
| Project/Area Number |
22350036
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Okayama University (2011-2012)
Kyushu University (2010) |
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Principal Investigator |
KANETA Takashi 岡山大学, 大学院・自然科学研究科, 教授 (20243909)
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| Project Period (FY) |
2010 – 2012
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| Keywords | キャピラリー電気泳動 / レーザー励起蛍光 / がん細胞 / タンパク質 / DNA、抗がん剤 / 多剤耐性タンパク質 |
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| Research Abstract |
：Biological cells consist of proteins, DNA, and a lot of small molecules, so high-performance separation analyticalmethods are important technologies for clarifying phenomena in biological cells at molecular levels. Therefore, this study aimed to the development of sensitive methods toseparate and determine drugs, bioactive molecules, proteins, and DNA, and application of the methods to the analysis of these components in biological cells. From the results obtained by the study, the developed methods are expected to be novel and useful techniques in the study of molecular biology.
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